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Post Info TOPIC: Collagen crosslinking with riboflavin and UVA-light in keratoconus


Phase Two

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Posts: 482
Date: Fri Sep 5 1:16 AM, 2008
Collagen crosslinking with riboflavin and UVA-light in keratoconus
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Collagen crosslinking with riboflavin and UVA-light in keratoconus

 

Reduced corneal mechanical stability in keratoconus and similar corneal diseases can be treated by photooxidative crosslinking of the corneal collagen. This method is currently undergoing clinical evaluation worldwide. To achieve high absorption of the irradiation energy in the cornea, riboflavin at a concentration of 0.1% and UVA light at a wavelength of 370 nm corresponding to the relative maximum of absorption of riboflavin (vitamin B2) is used. These therapeutic parameters were experimentally tested and have been proven clinically. Current data demonstrate that the therapeutic crosslinking procedure is safe when the important theoretical and clinical parameters are observed, and that progression of keratoconus can be prevented. In all, 80% of the published cases show a decrease in corneal curvature of about 2 D, which leads not only to stabilisation but also to an increase in visual acuity.

Ophthalmologe. 2008 Aug;105(8):785-96



-- Edited by QuintriX at 01:19, 2008-09-05

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Veteran Member

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Date: Sat Sep 12 8:10 AM, 2020
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Things has come a long way and in leaps and bounds - its continues to get optimized and studies continue (such as with oxygen supplementation).



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Posts: 16
Date: Tue Sep 22 10:28 PM, 2020
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A Not For Profit and the Worlds First Ever Eye Hospitals (Moorfields - NHS)

Keratoconus Treatment (NHS) Educational Video

Its good to be told of the risks. The risks are not often talked about at the outset from other providers videos so this is good, as well as it was nice seeing the straightforwardness, with what we here has known, that its ethnic minorities which have Keratoconus more.

 

 


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Date: Sat Sep 26 4:49 AM, 2020
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This webinar was hosted for professionals in the field. 

 

Treatment of early Keratoconus through Crosslinking can be an effective way to help [your] patients. Join this webinar hosted with SightLife and learn how to define the parameters for proper identification, treatment and management of Crosslinking.

Crosslinking Approaches for Keratoconus

Lecturer: Dr. Balamurali Ambati, Cornea Specialist, Pacific ClearVision Institution, Eugene Eye Care, Oregon, USA.

 



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Optometrist

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Posts: 10
Date: Fri Oct 23 11:48 AM, 2020
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In regards to the process in and of Crosslinking, Riboflavin, Oxygen, and UV-A light (the required measured amounts so that to) react to create covalent bonds between corneal stromal collagen fibers. The optimum and proper penetration of all three in to the corneal stroma is critical for successful CXL. Its getting nearly there/close in regards to keeping the Epithelium on.

https://crstodayeurope.com/articles/2020-oct/epi-on-cxl-whats-holding-it-back/?utm_campaign=Enewsletters&utm_medium=email&_hsmi=98048943&_hsenc=p2ANqtz-81JdFDapjyi4H51IlK_S1JSqAXSJp8ERip03pYQuu7gbyzz-TlnNRpPcio9XRgv1ignDEOMtgeI7dZdz0VTc84NOHIytUnVXH199ZPbOXZflzwSls&utm_content=98048943&utm_source=hs_email



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