All of us Vs Keratoconus


Members Login
Chatbox
Please log in to join the chat!
Post Info TOPIC: Baseline factors predicting the need for corneal crosslinking in patients with keratoconus


Member

Status: Offline
Posts: 20
Date: Sun Apr 26 6:04 AM, 2020
Baseline factors predicting the need for corneal crosslinking in patients with keratoconus
Permalink   
 


Baseline factors predicting the need for corneal crosslinking in patients with keratoconus

Naoko Kato ,Kazuno Negishi,Chikako Sakai,Kazuo Tsubota

Published: April 16, 2020https://doi.org/10.1371/journal.pone.0231439

 

Introduction

The primary purpose of crosslinking is to halt the progression of ectasia. We retrospectively assessed the condition of keratoconus patients who were followed-up at least twice after the initial examination to evaluate keratoconus progression, to identify definitive factors to predict a later need for corneal crosslinking (CXL).

 

Methods

The medical charts of 158 eyes of 158 keratoconus patients (112 males and 46 females; mean age, 27.8 ± 11.7 years), who were followed up at the Department of Ophthalmology, Keio University School of Medicine at least twice after the initial examination to evaluate keratoconus progression were retrospectively reviewed. Best-spectacle corrected visual acuity, intraocular pressure, steepest corneal axis on the anterior float (Ks), thinnest corneal thickness according to Pentacam® HR, and corneal endothelial cell density were assessed. Gender, age, onset age of keratoconus, history of atopic dermatitis, and Pentacam® indices were also recorded. CXL was performed when the eye showed significant keratoconus progression, an increase in the steepest keratometric value, or an increase in the spherical equivalent or cylinder power of the manifest refraction by more than 1.0 D versus the respective values 2 years prior. Predictor variables and the requirement for CXL were analyzed using logistic regression.

 

Results

Fifty-eight eyes required CXL treatment. The best predictor of the requirement for CXL was patient age, followed by the Pentacam® Rmin (the minimum sagittal curvature evaluated by Pentacam®) value. The incidence of CXL was 86.4% in the < 20 years age group, with an Rmin of 5.73 mm, whereas 10.8% in the 27 years age group with an Rmin > 5.73 mm underwent treatment.

 

Conclusions

An age of < 20 years and an Rmin value of 5.73 mm predicted keratoconus progression and the requirement for CXL treatment in the near future.



__________________


Member

Status: Offline
Posts: 6
Date: Sun Apr 26 6:15 AM, 2020
Permalink   
 

Thanks for your post.

Now if it could possible to use a smartphone with this approach which you posted on, that may be a further game changer.

"Nowadays smartphone utilization for disease diagnosis and remote health care applications has become promising

due to their ubiquity. Here, a novel convolutional neural network method for detecting keratoconus that is wholly

implemented on a smartphone is proposed. The proposed method provides accurate detection of over 72.9% for

all stages of keratoconus. Preliminary results indicate 90%, 83%, 64% and 52% detection rate for severe, advanced,

moderate and mild stages of disease, respectively."

I uploaded the article to this post. 



Attachments
__________________


Member

Status: Offline
Posts: 20
Date: Sun Apr 26 7:06 AM, 2020
Permalink   
 

It is uplifting both of the developments going on! I hope they will fandango! biggrin



__________________
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.

Post to Digg Post to Del.icio.us

www.kcfreedom.org

Knowledge Works