📈 Recent Scholarly Literature Across An Array of Publishing Indexes and Disciplines


RiTe conjugate mediated corneal collagen crosslinking, a novel therapeutic intervention for keratoconus–In vitro and in vivo study

H Rohira, S Shankar, S Yadav, PP Srivastava… - International Journal of …, 2024
Corneal collagen crosslinking (CXL) is an effective method to halt the disease
progression of keratoconus, a progressive corneal dystrophy leading to cone
shaped cornea. Despite the efficacy of standard protocol, the concerning step of this …
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[PDF] Comparison of keratoplasty outcomes at the scar versus edema stages of keratoconus

Y Chen, Z You, C Wang, R Gao, K Zhang - Arq Bras Oftalmol, 2024
… Keratoconus is a dilated corneal disorder in which the local corneal stroma
becomes thinner, … Acute corneal edema is a keratoconus condition that results
from the Descemet membrane … This study examined the outcomes of two …
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Corneal Endothelial Cell Volume Regulation Disorders in Keratoconus

IM Kuseina, LE Katkova, GS Baturina, IG Palchikova… - … ), Supplement Series A …, 2024
The study of the permeability to water and urea of plasma membranes of endothelial
cells of the normal cornea and cornea with a pronounced form of keratoconus was
carried out. Human corneal endothelial cells were obtained from surgical material …
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Evaluation of the results of contact lens assisted corneal cross-linking treatment in keratoconus patients with thin corneas

F Safalı, SY Ocak, BD Argon, G Karaca, MN Elçioğlu - Japanese Journal of …, 2024
Purpose We aimed to compare the efficacy and safety of accelerated contact lens-assisted
cross-linking (CA-CXL) with Lotrafilcon B and Comfilcon A lenses in keratoconus (KC)
patients with thin corneas. Study Design Retrospective, single-center study …
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[PDF] A novel posterior keratoconus with osteogenesis imperfecta by mutation in COL1A1

H Wu, X Shi, H Shi, L Liu, H Xu, L Hou, R Huang… - 2024
… Posterior keratoconus is a rare, non-progressive corneal condition in the posterior
surface of the cornea. Also known as keratoconus posticus, it is … The
manifestations in OI patients have not been well studied in the case of keratoconus …
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Retracted: Keratoconus Classification with Convolutional Neural Networks Using Segmentation and Index Quantification of Eye Topography Images by Particle …

BMR International - BioMed Research International, 2024
Retracted: Keratoconus Classification with Convolutional Neural Networks Using
Segmentation and Index Quantification of Eye Topography Images by Particle Swarm
Optimisation - PMC … Retracted: Keratoconus Classification with Convolutional Neural …
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… Retinal Blood Vessel Densities Measured by Optical Coherence Tomography Angiography in Keratoconus Patients Are Negatively Correlated with Keratoconus …

MD Leclaire, JJ Storp, L Lahme, EL Esser, N Eter… - Diagnostics, 2024
… Keratoconus (KC) is the most common corneal ectasia. Optical coherence
tomography angiography (OCT-A) is a relatively new non-invasive imaging technique
that allows the visualization and quantification of retinal and choriocapillary blood …
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[HTML] Criteria for patient selection and indication for intracorneal ring segments in keratoconus

A Vega, JL Alió - Eye and Vision, 2024
… to classify keratoconus [5]. In this publication, we aim to propose a better
approach of different treatments that are available for keratoconus … term result
after ICR implantation in the treatment of keratoconus, we decided to study patients …
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[HTML] Balanced activation of Nrf-2/ARE mediates the protective effect of sulforaphane on keratoconus in the cell mechanical microenvironment

R Liu, R Ma, X Yan - Scientific Reports, 2024
Keratoconus (KC) is a progressive degenerative disease that usually occurs
bilaterally and is characterized by corneal thinning and apical protrusion of the
cornea. Oxidative stress is an indicator of the accumulation of reactive oxygen …
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[PDF] Keratoconus: exploring fundamentals and future perspectives–a comprehensive systematic review

S Niazi, Z Gatzioufas, F Doroodgar, O Findl… - Therapeutic Advances in …, 2024
… Artificial intelligence has changed how we treat the eye disease keratoconus in
recent years. This study examines the many keratoconus therapies available, … The
idea behind using artificial intelligence is to help patients see better and treat …
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Barriers to the Diagnosis and Management of Keratoconus Among Optometrists in Kenya [Response to Letter]

ZA Rashid, VR Moodley, KP Mashige, KE Agho - Clinical Optometry, 2024
We reviewed the Letter to the Editor by Mahdi Sadeghi and Sabrina Shahid which
refers to our published article "Barriers to the Diagnosis and Management of
Keratoconus Among Optometrists in Kenya" 1 and their interest is noted. However …
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Efficacy comparison of combining cross-linking and refractive laser ablation in progressive keratoconus: a network meta-analysis of short-term outcomes and systemic …

A Achiron, T Yahalomi, B Knyazer, I Hecht, U Elbaz… - Canadian Journal of …, 2024
Purpose This study aimed to assess the effect of combining corneal collagen cross-linking
(CXL) with refractive laser ablation techniques for the treatment of keratoconus, a
progressive corneal disorder. Methods We performed a systematic review and meta-analysis …
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Quantitative evaluation of morphological and functional changes in meibomian glands and lipid layer thickness in patients with and without keratoconus

X Hou, C Liu, Y Luo, N Yu, P Chen, J Zhuang, K Yu - Graefe's Archive for Clinical and …, 2024
… In this prospective, cross-sectional study, 164 eyes of 164 keratoconus patients
and 64 eyes of 64 age-matched control subjects were included. … of keratoconus.
Gland diameter may be a sensitive functional morphology metric of meibomian …
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Outcomes of accelerated corneal cross-linking for pediatric and adult keratoconus: a comparative study

A Bustamante-Arias, JC Hernandez-Camarena… - International Ophthalmology, 2024
Purpose To compare the visual, refractive, and topographic outcomes of a high
irradiance accelerated corneal crosslinking (ACXL) protocol after a 12-month follow-up
between pediatric and adult patients with progressive keratoconus (KC). Methods …
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The effect of transepithelial corneal collagen cross-linking treatment on optical quality of the cornea in keratoconus: 12-month clinical results

S Kaya Ergen, S Subaşı, B Yılmaz Tuğan, N Yüksel… - International Ophthalmology, 2024
… least 400 mm and axial topography pattern consistent with keratoconus. All 67
patients in the study were diagnosed with progressive keratoconus. The presence of
at least one of the following criteria was considered as progressive keratoconus: An …
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The effect of the Interocular Difference in Blur on Binocular Vision in Keratoconus

BL Marella - 2024
… Phase reversals due to HOAs in keratoconus deteriorated stereoacuity (t>3.479, p<0.007) …
In conclusion, the eye with lesser disease severity dominates binocular viewing in
keratoconus. … factors (contrast and phase shifts) could partially restore the …
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[HTML] Keratoconus: Tailored contact lens solutions optimise vision

V Wang, M Ziaei
… A family history of keratoconus, eczema, asthma, eye rubbing, allergy, Down
syndrome and other collagen vascular disorders are risk factors for developing
keratoconus. Patients at risk, particularly those with a family history, should be …
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[PDF] Genetic investigation in a four-generation Chinese family with congenital fibrosis of extraocular muscles and keratoconus

Q Lin, X Wang, X Zhan, X Peng, Y Wang, X Zhou - Heliyon, 2024
Here, we have reported the genetic and clinical characteristics of four generations of
a family patient from China with congenital fibrosis of extraocular muscles 1 (CFEOM1)
and keratoconus (KC). The history of diseases, clinical observations, and blood …
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[HTML] The candidate proteins associated with keratoconus: A meta-analysis and bioinformatic analysis

T Song, J Song, J Li, H Ben Hilal, X Li, P Feng, W Chen - PloS one, 2024
Purpose Keratoconus (KC) is a multifactorial disorder. This study aimed to conduct a
systematic meta-analysis to exclusively explore the candidate proteins associated
with KC pathogenesis. Methods Relevant literature published in the last ten years in …
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Clinical study of normal, keratoconus, and post-surgical corneas with phase decorrelation OCT

BJ Blackburn, L Asroui, I Tarib, D Dunukara… - Ophthalmic Technologies …, 2024
Several important diseases and treatments of the cornea present primarily on a
micromechanical level. Here, a technique called temporal phase decorrelation OCT
is used to observe micromechanical weakening in the cornea after refractive surgery …
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[HTML] Central and peripheral corneal sagittal height in keratoconus and healthy eyes

M Larrosa, J Gispets, N Lupón, G Cardona, A Sempere - Contact Lens and Anterior …, 2024
… peripheral z values were larger in keratoconus, rotational variations were
comparable between keratoconus and healthy eyes, suggesting that large diameter
spherical rigid corneal contact lenses may be an alternative to scleral lenses in …
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[PDF] Schirmer test type I evaluation before and after collagen cross linking for treatment of keratoconus

KAELA GabAllah, MF Saleh, SAM Farid
… of keratoconus conditions using isotonic Riboflavin and Ultraviolet-A light. This
comparative study included 60 patients suffering from keratoconus. … There are
improvements in Schirmer test results after 6 months of CXL for treatment of …
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[HTML] Severe ulcerative keratopathy following implantation of an acellular porcine corneal stromal lenticule in a patient with keratoconus

T Berger, U Schlötzer-Schrehardt, F Flockerzi, L Daas… - Contact Lens and Anterior …, 2024
Purpose To report a case of ulcerative keratopathy following implantation of
acellular porcine corneal stroma (APCS) in a patient with keratoconus (KC).
Methods A 58 year-old patient initially presented with an ulcerative keratopathy in …
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High-Fluence Epithelium-off Accelerated Pulsed Corneal Cross-linking (15 mW/cm2; 7.2 J/cm2) for Pediatric Keratoconus: A 3-Year Retrospective Analysis

R Fasciani, L Scartozzi, S Bruzio, G Di Stefano… - Journal of Refractive …, 2024
… CXL for progressive keratoconus was first introduced by Wollensak et al6 in 2003.
It is the first suc- cessful treatment modality to stop the progression of keratoconus by
increasing the intrinsic corneal biomechanical stability. Their original standard CXL …
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[PDF] Prevalence of Keratoconus in the Young Eastern Population of Saudi Arabia

A Khattak, A Altalhi, AB Alotaibi, AM Khattak - Cureus, 2024
Background: Keratoconus (KCN) is a progressive corneal ectasia that manifests at a
young age and significantly impacts vision and quality of life. Early diagnosis allows
for effective treatment with corneal collagen crosslinking, yet there is a lack of …
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Scheimpflug-Based Tomographic Risk Factors for the Development of Acute Corneal Hydrops in Keratoconus.

SN Yu, R Gad, R Kutler, D Trief - Cornea, 2024
Purpose The purpose of this study was to assess the risk factors that predispose
patients with keratoconus to develop acute corneal hydrops (ACH), including both
clinical and tomographic risk factors. We additionally describe tomographic changes …
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Estimated prevalence of keratoconus in the largest metropolitan area of Italy

M Lombardo, D Alunni Fegatelli, S Serrao, A Vestri… - European Journal of …, 2024
… This study reported a high estimated prevalence of keratoconus in a metropolitan
area of Italy, as found in recent studies in the Mediterranean and Middle East
countries. Screening for keratoconus is highly recommendable and easily feasible …
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Relationship between Conjunctival Impression Cytology, the Type of Eye Rubbing and the Stages of Keratoconus

LA Rodriguez, SE Guerrero, LA Rodriguez-Gutierrez… - 2024
… Keratoconus is a multifactorial disease where eye rubbing plays an important role
in disease progression. Persistent eye rubbing may … the index and middle finger
can lead to advanced stages of keratoconusKeratoconus stage IV was associated …
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[HTML] Mendelian Randomisation Analysis of Causal Association between Lifestyle, Health Factors, and Keratoconus

J Cheng, L Yang, Y Ye, L He, S Chen, J Wang - Bioengineering, 2024
Keratoconus (KC), a leading cause of vision impairment, has an unclear aetiology.
This study used Mendelian randomization (MR) to explore the causal links between
various factors (smoking, asthma, Down syndrome, inflammatory bowel disease …
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[HTML] Differences in anterior chamber depth in keratoconus patients with binocular very asymmetry ectasia

Z Wang, H Ma, Y Zhang, Y Yuan, Y Liu, Y Chen - BMC ophthalmology, 2024
… Keratoconus is a noninflammatory ectatic corneal disorder that is commonly
bilateral and usually asymmetrical, in which the ectatic cornea … and treatment of
keratoconus, and there are few studies of anterior chamber characteristics in the …
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M Nicholson, VM Singh, S Murthy, D Gatinel, S Pereira… - Indian Journal of …, 2024
This review analyzed all pertinent articles on keratoconus (KCN) and cataract
surgery. It covers preoperative planning, intraoperative considerations, and
postoperative management, with the aim of providing a simplified overview of …
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[PDF] Barriers to the Diagnosis and Management of Keratoconus Among Optometrists in Kenya

ZA Rashid, VR Moodley, KP Mashige, KE Agho - Clinical Optometry, 2024
Background Early diagnosis and management of keratoconus (KC) are important for
limiting visual complications of the disease. This study aimed to explore the
perspectives of optometrists on the barriers to effective diagnosis and management …
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[PDF] Variants in the ZNF469 gene in families with Brittle cornea syndrome and keratoconus

Q Lin, X Wang, T Han, X Peng, X Zhou - Heliyon, 2024
… variants and keratoconus. We recruited a four-generation BCS1 family and two
keratoconus families to explore pathogenic ZNF469 variants. Methods: This study
included 11 members from a family with BCS1, 2 families with keratoconus, 368 …
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[PDF] Spike sign–To predict the formation of big bubble in deep anterior lamellar keratoplasty in advanced keratoconus

S D'Souza, R Shetty - Indian Journal of Ophthalmology, 2024
Lamellar surgeries have revolutionized our understanding and practice of
keratoplasties. However, the learning curve in deep anterior lamellar keratoplasty (DALK)
makes it daunting for novice surgeons. This paper describes a unique intraoperative …
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[HTML] Outcomes of 320-degree intrastromal corneal ring segment implantation for advanced keratoconus

NN Chen, CC Sun - Taiwan Journal of Ophthalmology, 2024
PURPOSE: The purpose of this study is to investigate visual and tomographic
outcomes and complications of long-arc length intrastromal corneal ring segment (ICRS)
implantation for the treatment of advanced keratoconus. MATERIALS AND …
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[HTML] In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus

Y Zhao, Y Zhu, Y Yan, H Yang, J Liu, Y Lu, Y Li… - Translational Vision Science …, 2024
… biomechanics of an in vivo keratoconus model, and keratoconus after CXL
treatments in vivo. We discuss the biomechanical properties of the in vivo
keratoconus model and evaluate the changes in the biomechanical properties of the …
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[HTML] Biomechanical changes in keratoconus after customized stromal augmentation

S Niazi, JA del Barrio, F Doroodgar, A Sanginabadi… - Taiwan Journal of …, 2024
… Diagnostic ability of corneal shape and biomechanical parameters for detecting
frank keratoconus. Cornea 2018;37:1025‑34. 10. … Comparison of different corneal
imaging modalities using artificial intelligence for diagnosis of keratoconus: A …
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A Cross-Sectional Analysis to Assess the Role of Atopy in Keratoconus Among Saudi Population [Corrigendum]

II Abuallut, AR Alomaish, AM Arishy, MA Mashragi… - International Journal of …, 2024
The International Journal of General Medicine is an international, peer-reviewed
open-access journal that focuses on general and internal medicine, pathogenesis,
epidemiology, diagnosis, monitoring and treatment protocols. The journal is …
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Differentially expressed microRNAs targeting genes in key pathways in keratoconus

DM Nowak-Malczewska, J Swierkowska, M Gajecka - Frontiers in Genetics
Introduction: Keratoconus (KTCN) is a corneal ectasia, characterized by a
progressive thinning and protrusion of the cornea, with a complex etiology involving
genetic, behavioral, lifestyle, and environmental factors. Previous studies indicated …
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[HTML] Expression of Tissue Inhibitors of Metalloproteinases (TIMP-1, TIMP-2, TIMP-3, TIMP-4) in Blood Serum of Patients with Keratoconus

M Nowak-Wąs, P Wąs, Z Czuba, R Wojnicz… - Journal of Clinical Medicine, 2024
… Clinical keratoconus was diagnosed in 134 eyes and subclinical keratoconus in
32 companion eyes. The severity of keratoconus was assessed based on the Amsler–Krumeich
classification. Most eyes with keratoconus showed the first or second degree of …
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[PDF] Descemetic Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty in Advanced Keratoconus: Comparison of Visual and Refractive Outcomes

L Spadea, L Di Genova, E Trovato Battagliola… - Therapeutics and Clinical …, 2024
… This study enrolled eyes affected by keratoconus with preoperative mean
keratometry ≥60 diopters (D) that were treated with either Descemetic DALK (30
eyes) or PK (29 eyes) by using always the same corneal diameters (8.00mm …
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Diagnostic Importance of OCT Pachymetry in Keratoconus

KK Benca, M Javorka, R Vida, J Halička, M Kralik… - Ceska a slovenska …, 2024
Aims To demonstrate changes in distance and near fusional vergence measured
with prism bars, while compensating for present heterophoria using current
ametropia correction. In addition, to determine the differences in values of the AC/A …
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[PDF] Evaluation of ocular surface features following corneal collagen cross-linking treatment in keratoconus patients: 24-month results

GS Vural, ES Sari, A Yazici, C Guler
… For this reason, we followed ocular surface parameters in keratoconus patients
until 24 months after CXL and compared them with pre-… The keratoconus patients
who have Grade 1 or 2 keratoconus according to the Amsler-Krumeich keratoconus …
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Pediatric keratoconus epidemiology: a systematic scoping review

LO Hansen, R Garcia, FB Cresta, AAM Torricelli… - International Ophthalmology, 2024
Background Pediatric keratoconus (pediatric KC) causes progressive deformation of
the cornea in children and adolescents, leading to a gradual loss of vision and a
need for rehabilitation. However, new treatments may halt the disease and prevent …
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Revisiting rabbit models for keratoconus: A long-term study on collagenase-induced disease progression

S Shankar, M Thacker, A Sahoo, AR Aindla, KR Padala… - Experimental Eye Research, 2024
Keratoconus (KC) is one of the degenerative corneal disorders consequential of
degradation of network of collagen fibrils in cornea leading to thinning and cone
shaped cornea. Various studies have established animal models of KC by inducing …
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Detecting Keratoconus in Primary Healthcare: What general practitioners could do? Poster Presentation-Case Report-General practitioner

MK Akbar, CP Samira - Ophthalmologica Indonesiana, 2023
… Children with keratoconus experience faster disease progression and significant
visual impairment at diagnosis, impacting their quality of … keratoconus with
amblyopia and was referred to an ophthalmologist for further examination and …
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CAN RIGID GAS PERMEABLE (RGP) CONTACT LENS BE THE BEST OPTION FOR A KERATOCONUS PATIENT? Poster Presentation-Case Report-Resident

DF DWIMARTA, ANI ISMAIL, EVA KUMALASARI - Ophthalmologica Indonesiana, 2023
Introduction : Keratoconus is a condition of cone-shaped cornea caused by stromal
thinning. This disorder leads to visual disturbance due to irregular astigmatism,
myopia, and corneal protrusion. A severe irregular astigmatism must be corrected by …
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Rigid Gas Permeable (RGP) as Keratoconus Management After Corneal Collagen Cross-Linking (CXL) Procedure: a Case Report: Poster Presentation-Case Report …

MLA Sanusi, K Satari, JS Hutabarat, IR Musa, SN Sirait - Ophthalmologica …, 2023
… are the mainstay for keratoconus patients and widely used. This case report
presents RGP as a management for keratoconus after Corneal Collagen Cross-
Linking (CXL) procedure. Case Illustration : A 22-year-old woman diagnosed with …
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Corneal Collagen Cross-Linking (CXL) in Pediatric Keratoconus: Changes in Visual Acuity and Biomechanical Properties: Visual Acuity and Biomechanical Properties

G Sulaksmono - Ophthalmologica Indonesiana, 2023
Abstract Introduction & Objectives : Keratoconus is a progressive disease that
changes the … study that included all pediatric keratoconus patients without any
underlying disease that … Overall, CXL was safe and significantly improve UCVA …
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Intrastromal corneal ring segments for keratoconus patients: up to 12 years follow up

M Al Bdour, M Abu-Ameerh, A Gharaibeh, R AlQudah… - International Ophthalmology, 2024
… This study represents the largest follow up for ICRS implanted in keratoconus
patients. Improvement of … keratoconus patients recruited from 2008 to 2010 and
underwent ICRS implantation. In this study, we reported the long-term outcome of …
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[HTML] Binocular vision parameters and visual performance in bilateral keratoconus corrected with spectacles versus rigid gas-permeable contact lenses

LF Barba–Gallardo, LM Jaramillo-Trejos… - Journal of Optometry, 2024
Purpose To analyze binocular vision of individuals aged 18 to 35 years diagnosed
with keratoconus, utilizing spectacles and rigid gas-permeable (RGP) contact lenses.
Research was led by the Universidad Autónoma de Aguascalientes, México and …
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[PDF] Keratoconus characteristics and associations: A cross-sectional keratoconus study in western India (CKSWI)

Z Shah, D Purohit, P Danayak - Indian Journal of Ophthalmology, 2024
Purpose: To study the clinical and tomographic characteristics and associations of
keratoconus (KC) patients visiting a tertiary eye care hospital. Methods: This was a
cross-sectional, observational study that included 242 newly diagnosed clinical KC …
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Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes

R Vilares-Morgado, AM Ferreira, AM Cunha, R Moreira… - Clinical Ophthalmology, 2024
… Keratoconus treatment has improved significantly in recent years, with the
development of … , in patients with progressive keratoconus who underwent a
single treatment of TE-ACXL. … Retrospective, single-center, observational, cohort …
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[HTML] A current review on keratoconus

G Lahkar, G Paul - Journal of Ophthalmic Research and Practice, 2023
… Subclinical keratoconus is a term used to describe an eye having topographic
signs of keratoconus with normal corneal slit-lamp findings, … decreased in
keratoconus. It is a valuable tool to differentiate forme fruste keratoconus from …
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Assessment of Health Disparities and Barriers to Accessing Keratoconus and Crosslinking at a Tertiary Referral Center

L Angelo, A Gokul, H Wadhwa, CNJ McGhee, M Ziaei - Cornea, 2024
… Keratoconus is a progressive noninflammatory corneal ectasia, often diagnosed
during youth. This disease process causes the cornea to … and successful
treatment for preventing the progression of keratoconusKeratoconus typically …
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[HTML] Accelerated Corneal Cross-linking in Pediatric Patients with Progressive Keratoconus: 12-Month Follow-up Results

S Dervişoğulları, A Pelit - Nigerian Journal of Clinical Practice, 2024
… In this study, case series of patients 18 years old or younger with progressive
keratoconus who underwent accelerated CXL were observed. All consecutive
patients underwent accelerated CXL with setting of 9 mW/cm 2 for 10-minute …
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[HTML] A Novel approach for Corneal Remodeling of Laser Asymmetric Keratectomy with Collagen Cross Linking in Patients with Keratoconus Suspect

JS Min, D Lee, SS Lee, PM Min - The Open Ophthalmology Journal, 2024
Background True Keratoconus Suspect (KCS) is an absolute contraindication to
LASIK or Photorefractive Keratectomy (PRK) due to postoperative ectasia. Objective
To evaluate the effectiveness of laser asymmetric keratectomy with collagen cross-linking …
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[PDF] Comparative posterior corneal profile of keratoconus hydrops versus Haab's striae in congenital glaucoma

S Mandal, A Singh, S Sen, JS Titiyal, V Gupta, S Gupta - Indian Journal of Ophthalmology
Keratoconus eyes develop corneal decompensation more often compared to eyes
with primary congenital glaucoma (PCG) following Descemet's membrane (DM) tear.
This study was conducted to compare the posterior corneal morphology in areas …
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[PDF] Analysis of Scheimpflug Tomography Parameters for Detecting Subclinical Keratoconus in the Fellow Eyes of Patients with Unilateral Keratoconus in the Eastern …

A Al Somali, H Najmi, H Alsawadi, H Alsawadi… - Clinical Ophthalmology, 2024
… Normal fellow eyes in patients with unilateral keratoconus were found to exhibit
the mildest form of subclinical keratoconus. The … keratoconus and normal eyes,
implying the need for multimodal imaging techniques for the optimal early detection …
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Toward Keratoconus Diagnosis: Dataset Creation and AI Network Examination

P Ghorbani, MJ Ahmadi, SS Naseri, M Keshavarz… - 2023 11th RSI International …, 2023
… Diagnosing keratoconus (KC) is essential due to its effect on refractive surgeries
like LASIK … AI can significantly assist in the automatic and accurate diagnosis of
keratoconus. For this … This method facilitates an accurate diagnosis of …
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AI-Driven Keratoconus Detection: Integrating Medical Insights for Enhanced Diagnosis

M Keshavarz, MJ Ahmadi, SS Naseri, P Ghorbani… - 2023 11th RSI International …, 2023
… of keratoconus as a main ocular disorder is imperative for reducing the risk of
vision blurring and potential blindness. Additionally, keratoconus (… This study
introduces an image dataset acquired by the Pentacam device, which is commonly …
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[HTML] Lenticule addition keratoplasty for the treatment of keratoconus: A systematic review and critical considerations

Y Liu, Y He, Y Deng, L Wang - Indian Journal of Ophthalmology, 2024
… Keratoconus is a corneal disorder characterized by the progressive thinning and
bulging of … as conventional surgical methods for advanced keratoconus are
limited by relatively high rates … Keratoconus is a multifactorial disease …
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[PDF] A Comparison of Black and Non-Black Patients in the Presentation and Treatment of Keratoconus

M Christensen, J Kartchner, M Giegengack… - Clinical Ophthalmology, 2024
Purpose Patients with advanced keratoconus (KCN) are less likely to benefit from
corneal cross-linking and may require a partial or full thickness keratoplasty. This
study aimed to determine whether racial disparities exist in the clinical presentation …
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[HTML] Headache Attributed to Refractive Error: Improvement after Topography-Guided Photorefractive Keratectomy with Corneal Cross-Linking in Patients with Keratoconus

NTH Khoo, B Burgos-Blasco, A Antoniou, B Jenkins… - Journal of Clinical Medicine, 2024
… to refractive errors (HARE) in keratoconus. Methods: Patients diagnosed with
keratoconus undergoing TGPRK for refractive correction were … Conclusions:
Surgical correction of irregular astigmatism in patients with keratoconus can …
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[HTML] In vivo confocal microscopy evaluation of infiltrated immune cells in corneal stroma treated with cell therapy in advanced keratoconus

M El Zarif, K Abdul Jawad, JL Alió, N Makdissy… - Journal of Ophthalmic …, 2024
This study investigates immune cell (ICs) infiltration in advanced keratoconus
patients undergoing autologous adipose-derived adult stem cell (ADASC) therapy
with recellularized human donor corneal laminas (CL). A prospective clinical trial …
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[HTML] Mini review: human clinical studies of stem cell therapy in keratoconus

M Ahadi, S Ramin, A Abbasi, H Tahmouri, SB Hosseini - BMC ophthalmology, 2024
… , there are limited clinical studies in keratoconus. These studies showed
promising results of … In this article, we tried to review different aspects of
keratoconus stem cell therapy, including … of keratoconus, the goal of intrastromal …
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[HTML] Improving early detection of keratoconus by Non Contact Tonometry. A computational study and new biomarkers proposal

E Redaelli, M Nana, B Calvo, JFR Matas, G Luraghi… - Journal of the Mechanical …, 2024
… Keratoconus is a progressive ocular disorder affecting the corneal tissue, leading
to irregular astigmatism and decreased visual acuity. The architectural organization
of corneal tissue is altered in keratoconus, … and improve the diagnosis of …
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[HTML] … Changes of Cornea Volume Measured by Means of Anterior Segment-Optical Coherence Tomography in Patients with Stable and Progressive Keratoconus

S Vaccaro, C Vivarelli, AC Yu, N Pecora, G Lionetti… - Life, 2024
… Consecutive patients affected by keratoconus were evaluated by means of
anterior segment-optical coherence … keratoconus eyes have yet to be investigated,
we sought to evaluate, over time, these modifications in patients with both stable and …
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[HTML] Genetic variants in the FOXO1 and ZNF469 genes are associated with keratoconus in Sweden: a case-control study

W Wonneberger, B Sterner, U MacLean, M Claesson… - BMC Ophthalmology, 2024
Keratoconus (KC) is characterized by pathological thinning and bulging of the
cornea that may lead to visual impairment. The etiology of sporadic KC remains
enigmatic despite intensive research in recent decades. The purpose of this study …
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Keratoconus: Ocular surface considerations, from bench to bedside

F Doroodgar, S Niazi - Acta Ophthalmologica, 2024
Aims/Purpose: This comprehensive systematic narrative study is aimed to describe
the close interactions between the ocular surface and keratoconus with its vast
spectrum of diagnostic and treatment techniques, both basic and clinical. Methods …
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Is it really keratoconus‐topographic mimicry

A Wykrota, B Seitz, E Flockerzi - Acta Ophthalmologica, 2024
… keratoconus configuration, but in which objectifiable no keratoconus exists and
thus a so-called pseudo-keratoconus is present. … Conclusions: This case series
shows that different corneal pathologies can imitate a topographic keratoconus …
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Morphogeometric characterization in keratoconus according to the RETICS grading system

CPT Jaimes, E Megiddo, C Gomez, A Moya… - Acta Ophthalmologica, 2024
… Aims/Purpose: Keratoconus progression characterizes by corneal thinning
resulting in irregular astigmatism and visual impairment. In the … variables in
healthy corneas and keratoconus. RETICS grading system was used to characterize …
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Comparison of waveform‐derived ORA parameters in clinical keratoconus, subclinical keratoconus and healthy subjects

K Atay, O Özalp, E Atalay - Acta Ophthalmologica, 2024
Aims/Purpose: The aim of this study was to comparison of waveform‐derived Ocular
Response Analyser (ORA) parameters in clinical keratoconus (KC), subclinical
keratoconus (SKC) and healthy subjects. Methods: This retrospective comparative …
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Repeatability of ANTERION in subjects with keratoconus

MS Larraz, A Blasco‐Martinez - Acta Ophthalmologica, 2024
… Aims/Purpose: The aim of this study was to study the repeatability of ANTERION
in subjects diagnosed with keratoconus. Methods: The subjects selected had a
previous diagnosis of keratoconus. These subjects were divided into three groups …
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Big data enabled keratoconus care

JPO Li - Acta Ophthalmologica, 2024
… Keratoconus is a disorder affecting the cornea in which its normal round shape …
keratoconus getting worse. However there is limited reports of its long term safety in
large numbers and we reported one of the largest series in the world. We used data …
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Deep learning in early keratoconus/corneal ectasia

A Langenbucher - Acta Ophthalmologica, 2024
… Early detection of keratoconus in a screening environment is crucial as in this
stage several therapeutic options such as collagen … In this talk we focus on new
techniques of automatic identification of ectatic corneal diseases such as …
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The biomechanical e‐staging—In vivo assessment of corneal biomechanics in keratoconus

E Flockerzi, R Vinciguerra, MW Belin, P Vinciguerra… - Acta Ophthalmologica, 2024
Aims/Purpose: Keratoconus (KC) is biomechanically characterized by a decreased
resistance to deformation when compared to healthy corneas. The aim of this
presentation is to give an overview about the development and clinical application of …
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In‐vivo evaluation of corneal collagen fibrils pattern to detect Keratoconus

C Ancona, ML Passaro, M Airaldi, E Lipari, F Semeraro… - Acta Ophthalmologica, 2024
Aims/Purpose: The corneal stroma, is formed by fibrous connective tissue containing
collagen fibrils that are super‐organized in lamellae. In keratoconus (KC), intra‐lamellar
and inter‐lamellar disrupted organization causes a progressive thinning and corneal …
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Peripheral sterile corneal infiltrate after cross linking in keratoconus: A case report

R Ayad, D Ghizlane, R Chahir, L Ajdour - Acta Ophthalmologica, 2024
Aims/Purpose: The aim of our work is to describe the clinical aspect of sterile corneal
infiltrates after cross linking and to evaluate the risk factors involved in their
occurrence. Methods: We report the case of a young girl, followed for bilateral …
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[PDF] Influence of corneal diameter on the accuracy of corneal tomography in patients with forme fruste keratoconus or thin corneas

L Ding, L Niu, W Shi, X Zhou, Y Qian - Clinical and Experimental Optometry, 2024
… on the diagnostic accuracy of Pentacam tomographic indices in eyes with forme
fruste keratoconus (FFKC) and thin corneas. … of keratoconus suspicion. However,
owing to the ambiguity of the definition, there are no definitive criteria to help …
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[PDF] Keratoconus Treatment Using Femtosecond Laser–Assisted Innovative Intracorneal Ring–Supported Graft Surgery: A Pilot Investigation

K Jadidi, JL Alió, SA Mosavi, F Nejat, H Aghamolaei… - Journal of Refractive …, 2024
… keratoconus and its progression, there is still a need for ways to better reshape
the cornea, further improve visual acuity, and halt the progression of keratoconus. …
Moreover, ICR insertion can only be used for mild to moderate keratoconus, and is …
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[HTML] Analysis of Cytokine and Chemokine Level in Tear Film in Keratoconus Patients before and after Corneal Cross-Linking (CXL) Treatment

M Krok, E Wróblewska-Czajka, O Łach-Wojnarowicz… - International Journal of …, 2024
Keratoconus (KC) is a degenerative corneal disorder whose aetiology remains
unknown. The aim of our study was to analyse the expressions of cytokines and
chemokines in KC patients before and after specified time intervals after corneal …
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Tomographic characteristics of keratoconus in a sample of Yemeni patients Featured

MA Al-Ansi, NA Aldhaigi, HA Alakhlee
Background: Keratoconus is a non-inflammatory disorder that leads to visual
impairment. Early diagnosis and treatment save the vision of the patients. Aim: This
study aimed to identify tomographic characteristics of keratoconus in Yemeni patient …
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[HTML] Patterns in refractive error and treatment delay in keratoconus–An Australian study

S Bobba, A Wood, J Males, Y Kerdraon - Plos one, 2024
Keratoconus is the most common primary corneal ectasia and is associated with
significant morbidity. In its early stages, keratoconus is often … Early diagnosis of
keratoconus facilitates timely referral for treatments such as corneal collagen cross-linking …
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Accuracy of intraocular lens power formulas in eyes with keratoconus: Multi-center study in Japan

T Yokogawa, Y Mori, H Torii, S Goto, Y Hasegawa… - Graefe's Archive for Clinical …, 2024
… The MAE of the Barrett True-K for keratoconus, Kane keratoconus, and Kane
formulas … Keratoconus-specific formulas were more accurate than existing
formulas in Japanese eyes. The Barrett True-K formula for keratoconus had higher …
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[PDF] Balanced Activation of Nrf-2/ARE Mediates Sulforaphane's Protective Effect on Keratoconus in Cell Mechanical Microenvironment

R Liu, R Ma, X Yan - 2024
Keratoconus (KC) is a progressive degenerative disease that usually occurs
bilaterally and is characterized by corneal thinning and the apical protrusion of the
cornea. Oxidative stress is an indication of the accumulation of reactive oxygen …
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[PDF] Longitudinal Evaluation of Biomechanical Indices in Fellow Eyes of Patients With Keratoconus Classified as Having Very Asymmetric Ectasia With Normal Topography

B Kovalchuk, R Khoramnia, HS Son, J Meis, P Winkler… - Journal of Refractive …, 2024
… keratoconus registered in the keratoconus registry at the University Eye Clinic
Heidelberg between October 2020 and October 2022. A total of 513 patients with
keratoconus … unilateral keratoconus and fellow eyes with tomographically regular …
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M Khan, A Ageed - Cureus, 2024
Keratoconus (KC) incidence is on the increase. The advent of corneal-collagen cross-linking
(CXL) has revolutionized the management of KC. This systematic review looks at the
efficacy and complications of two novel treatments within CXL: Epithelial-On (Epi-On) …
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[PDF] Awareness of Keratoconus and Its Relationship With Eye Rubbing Among the Population of the Eastern Province of Saudi Arabia

A AlSomali, D Almithn, A Alamer, A Al-Omair… - Cureus, 2024
… Aim: This study aims to assess the awareness level of keratoconus and its
relation to eye rubbing … keratoconus among participants in the Eastern Province of
Saudi Arabia, our research revealed a total of 101 (26%) participants had an overall …
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[HTML] Keratoconus cone location influences ocular biomechanical parameters measured by the Ocular Response Analyzer

PT Yuhas, MM Fortman, AM Mahmoud, CJ Roberts - Eye and Vision, 2024
Background Keratoconus is characterized by asymmetry in the biomechanical
properties of the cornea, with focal weakness in the area of cone formation. We
tested the hypothesis that centrally-measured biomechanical parameters differ …
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[HTML] Artificial intelligence as diagnostic modality for keratoconus: A systematic review and meta-analysis

A Afifah, F Syafira, PM Afladhanti, D Dharmawidiarini - Journal of Taibah University …, 2024
Artificial intelligence (AI) has been utilized to enhance diagnostic management and
guide treatment. The use of AI as a sophisticated diagnostic modality has not only
improved the feature of cornea evaluation in ocular imaging but also has unlocked …
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[HTML] Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium

R Ning, Y Wang, Z Xu, I Gustafsson, J Li, G Savini… - Eye and Vision, 2024
… repeatability of the measurements and the keratoconus disease severity, the
repeatability was assessed in patients with varying degrees of keratoconus [22, 23].
Here, we provided cut-off criteria for the assessment of progressive patients with …
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[HTML] Keratoconus overview: History, etiology, and diagnosis

A Morgenstern - 2023
… Keratoconus is a disease of the cornea that, if left untreated, can lead to loss of
vision, decrease in quality of life, and potentially blindness. As optometrists, we are
the gatekeepers of the management of keratoconus, … Patients who present with …
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[HTML] Comparative evaluation of methods for obtaining the stress-free geometry of keratoconus corneas with different levels of severity

C Gómez, DP Piñero, JL Alió, F Cavas - Computers in Biology and Medicine, 2023
… The patient-specific 3D geometric modelling used in this study for each
keratoconus severity grade was generated from a finite and discrete set of points
acquired by the Sirius tomograph vision algorithm (spatial point clouds …
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[HTML] Unilateral progressive keratoconus associated with ipsilateral craniofacial fibrous dysplasia treated with corneal cross-linking

AC Jiang, M Indaram - American Journal of Ophthalmology Case Reports, 2023
… In this report, we describe a case of unilateral keratoconus associated with
ipsilateral polyostotic fibrous dysplasia of the left frontal bone and orbital roof that
underwent successful stabilization of keratoconus progression after corneal …
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[PDF] Identification of Comparative Collagen Fibril Associated Changes in Normal and Keratoconus Corneas using Vibrational Optical Coherence Tomography and …

FH Silver, D Benedetto, T Deshmukh, NA Daher - Med Discover-ies, 2023
Vibrational Optical Coherence Tomography (VOCT) is a non-invasive technique that
uses infrared light and audible sound to characterize tissues noninvasively. We
have used VOCT in vivo to characterize the differences between control corneas …
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